This Week in Research
Home »May 1 - 7, 2023
RAb4A Control of Liver Dysfunction in a Mouse Model of Systemic Lupus Erythematosus
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Uncovering critical roles for retrotransposon-derived proteins in Ubiquilin-2 biology
Ubiquilin-2 is a protein that plays an essential role in regulating the cellular response to misfolded and damaged proteins. It is also involved in the degradation of proteins that are no longer needed by the cell. Mutations in Ubiquilin-2 are believed to be causal in Frontal Temporal Dementia and/or Huntington’s disease. Understanding its trafficking in cells, which can be facilitated by retrotransposon-derived proteins, is therefore important to understanding its biological function.
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Using an auxin-inducible degron to investigate rDNA transcription: Pol I subunits A34 and A49 are essential in mammalian cells, but not in yeast”
Hosted by: Bruce Knutson, PhD (315-464-8709)
Pharmacological inhibition of Protein Phosphatase-5 and induction of the extrinsic apoptotic pathway in kidney cancer
Thesis Defense Seminar
Distinct interaction modes for the eukaryotic RNA polymerase alpha-like subunits and implications for disease modeling
Thesis Defense Seminar
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