Successful candidates will augment existing capabilities and expertise in regenerative medicine at Binghamton University and Upstate Medical University, build on ongoing research at both campuses and further strengthen and grow cross-institutional collaborations. 

Develop and implement a robust plan to synergize and accelerate research partnerships between the Center of Biomanufacturing for Regenerative Medicine (CBRM) led by Watson Colleges Biomedical Engineering Department, Binghamton University's School of Pharmacy and Pharmaceutical Sciences, and the Basic Science and Clinical Departments at Upstate Medical University.

• Lab maintenance tasks
• Mouse breeding & genotyping
• Mammalian cell culture

• Utilize western blotting, qPCR methods
• Perform neurobehavioral testing in mice
• Perform irradiation, bone marrow isolation, bone marrow transplantation, blood collection, flow cytometry, immunohistochemistry

• Perform tick identification, RNA extraction, and multiplex RT-PCR pathogen testing
• Analyze Citizen Science tick surveillance and other tick testing data
• As needed, help with tick collection at field sites
• Assist in developing public/social media/website messaging content (video/audio/text) for the Citizen Science Tick surveillance program

• Performs molecular, biochemical, cell biological approaches (qPCR, in situ hybridization, immunohistochemistry, Western blot, tissue culture, etc.) to obtain data relevant to project
• Generates, analyzes, and reports research results
• Responsible for the breeding, identification (genotyping), and accurate record keeping of the laboratory's mouse colony

• Responsible for coordinating various research trials for the Department of Urology, including early to late-phase FDA-regulated trials
• Ensure compliance with federal guidelines
• Enroll, screen, and register patients for clinical research trials; collect and submit clinical trial patient data

• Understand the requirements and objectives of each clinical protocol; research questions regarding protocol or eligibility for physicians or support staff
• Follow patient course of treatment by ensuring all procedures are being conducted per protocol
• Collaborates with principal investigators and other departmental staff in the delivery and improvement of services by identifying problems, analyzing work processes, recommending improvements, and participating in the implementation of changes in workflow

• Learn, if they don't already know, quantitative fluorescence microscopy techniques in living cells, including but not limited to, computer coding for quantitative analysis (using MATLAB, R, or Python), cell culture, molecular biology and the generation of transgenic model organisms
• Maintain several advanced fluorescence microscopes, as well as train students and postdocs in their use
• Train students and postdocs in molecular and cell biology and protein biochemistry techniques
• Assist the PI in writing grant proposals, draft manuscripts and research animal protocols

• Responsible for ordering lab equipment and reagents, and assisting in the maintenance of the transgenic mouse colony and performing experiments
• Assist with in vivo regeneration experiments, including retinal dissections, tissue sectioning, immunohistochemistry, tissue imaging and analysis

• Responsible for ordering lab equipment, supplies, reagents and contributing to the maintenance of the transgenic mouse colony, and performing experiments
• Assistance with in vivo regeneration experiments, including retinal dissections, tissue sectioning, immunohistochemistry, tissue imaging and analysis, and flow cytometry

• Maintaining the mouse colony, organizing the lab, and utilizing molecular biological techniques, like DNA isolation, PCR, and gel electrophoresis
• Set up breeding pairs, take tissue samples, and identify mice for experimental analysis
• Learn how to cryostat section, immunostain, perform microscopy/imaging, and count cells for cellular analysis

• Responsible for the maintenance of the mouse colony and perform experimental work to further the goals of the laboratory
• Setting up timed matings, breeding animals to maintain lines, collecting tissue samples, molecular analysis of samples (genotyping, isolating DNA, PCR, performing DNA electrophoresis), and accurate record keeping
• Assist with electroporation experiments, induction of gene expression experiments, primary tissue culture, tissue preparation and processing for immunochemistry (frozen sections and vibratome sections) and immunohistochemistry

• Monitoring supplies, maintenance of animal colony, and preparation of lab reagents
• Gain expertise in a variety of experimental techniques, including preparation of tissue samples, tissue culture, fluorescence and confocal microscopy, DNA, RNA, and protein analyses by gel electrophoresis, western blotting, PCR, qCPR, and sequence analysis
• Engage in data interpretation and analysis, and report preparation

• Responsible for conducting research under the supervision of PI and assisting other group members with their research projects
• Design and conduct experiments independently in biochemistry and related fields
• Summarize results, present data, trouble-shoot and draft manuscript for publication

Perform experiments, data analysis, record keeping, administrative support and lab maintenance

Preparation of tissue samples, tissue culture, fluorescence and confocal microscopy, DNA, RNA and protein analyses by gel electrophoresis, western blotting and PCR

• Study the mechanisms that coordinate the dynamic rearrangements of the actin and microtubule cytoskeletons by reconsidering the roles of classic cytoskeletal regulators in regulating the "other" polymer system or both simultaneously
• Focus on collaborative mechanisms of actin-microtubule crosstalk initiated at actin filament and microtubule plus-end associated proteins and cell- and in vitro biochemistry-based tools to decipher these mechanisms
• We have also developed two important and valuable tools for the cell biology community, including:

1. A cost-effective and straightforward way to produce untagged and non-muscle isoforms of human actin from budding yeast
2. The first fully functional fluorescent profilin probe that can be used in biochemical experiments or titrated to resolve single molecules of profilin in cells

• By combining these tools with additional molecular biology techniques, reverse genetics, and quantitative cellular approaches (e.g., CRISPR, single-particle tracking, plating cells on micropatterns) we can potently dissect complex biological systems at high resolution (low nm). This broadly applicable approach allows us to define important molecular mechanisms in vitro and then assess their biological importance in living cells

• Responsible for successfully conduct experiments such as Western blotting, cell culture, PCR, tissue sectioning, confocal microscopy, and others
• Ensure general operation and organization of the lab, including obtaining quotes and ordering lab supplies, working with chemicals and biohazards, and maintaining lab safety protocols

• Provide technical support for a research lab that studies developmental neural plasticity
• Perform experiments, data analysis, record keeping, administrative support, and lab maintenance

• Assist faculty members and lab personnel in conducting research and carrying out research experiments and summarization of data
• Perform experiments, data analysis, record keeping, administrative support, and lab maintenance
• Teach lab procedures and experimental protocol to students and technicians

• Pre-screen, Screen, and enroll research participants in outpatient ALS clinical trials
• Schedule and conduct follow up research appointments for clinical trial participants
• Data collection and entry into paper and electronic databases

• Work with faculty, department administrators, and institutional leadership to submit applications for sponsored funding
• Review sponsored funding opportunities and interpret guidelines
• Facilitate grant preparation and be the primary contact for the final review and submission process

• Study the mechanisms that coordinate the dynamic rearrangements of the actin and microtubule cytoskeletons by reconsidering the roles of classic cytoskeletal regulators in regulating the "other" polymer system or both simultaneously
• Focus on collaborative mechanisms of actin-microtubule crosstalk initiated at actin filament and microtubule plus-end associated proteins and cell- and in vitro biochemistry-based tools to decipher these mechanisms
• We have also developed two important and valuable tools for the cell biology community, including:

1. A cost-effective and straightforward way to produce untagged and non-muscle isoforms of human actin from budding yeast
2. The first fully functional fluorescent profilin probe that can be used in biochemical experiments or titrated to resolve single molecules of profilin in cells

• By combining these tools with additional molecular biology techniques, reverse genetics, and quantitative cellular approaches (e.g., CRISPR, single-particle tracking, plating cells on micropatterns) we can potently dissect complex biological systems at high resolution (low nm). This broadly applicable approach allows us to define important molecular mechanisms in vitro and then assess their biological importance in living cells